NeuroMab™ Anti-FGFR1 BBB Shuttle Antibody(NRZP-1022-ZP3896)

Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Rat

Applications

WB; ELISA; In Vitro; In Vivo; ADCC; Antagonist

Relevant Diseases

Multiple Sclerosis; Glioma

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

FGFR1

Official Name

FGFR1

Full Name

Fibroblast Growth Factor Receptor 1

Alternative Names

Fibroblast Growth Factor Receptor 1; Basic Fibroblast Growth Factor Receptor 1; Fms-Related Tyrosine Kinase 2; Proto-Oncogene C-Fgr; EC 2.7.10.1; BFGF-R-1; FGFR-1; N-SAM; BFGFR; FGFBR; FLT-2; HBGFR; FLT2; CEK; FLG;

Product Pictures

ELISA

Figure 1 shows the mapping of mAb #A08, mAb #A05, and a control antibody (anti-egg lysozyme) to the domain of lg-D2 by ELISA. The optical density measured at 450 nm was plotted against antibody concentration (using the Logio scale).

Publications