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Creative Biolabs

NeuroMab™ Anti-TNFα Antibody(NRP-0422-P788)

[CAT#: NRP-0422-P788]

A functional antibody raised against Human TNFα.

Host Species:
Mouse
Species Reactivity:
Human
Applications:
ELISA; Cyt; In Vitro; In Vivo

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Product Overview

Description

The antibody binds to human tumor necrosis factor alpha (TNF) and is useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

ELISA; Cyt; In Vitro; In Vivo

Relevant Diseases

Neuroinflammation
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

TNFα

Official Name

TNF-α

Full Name

TNF-alpha

Alternative Names

TNF; DIF; TNF-alpha; TNFA; TNFSF2; Tumour necrosis factor; TNF-α; tumor necrosis factor; TNLG1F; Tumor necrosis factor alpha

Gene ID

7124(Human); 21926(Mouse)

Uniprot ID

P01375(Human); P06804(Mouse)
Product Pictures
ELISA

Figure 1 shows the titration of TNF using MAb 1.

ELISA

Figure 2 shows the TNF MAb 1 scatchard plot and affinity determination.

Cyt

Figure 3 shows the effect of anti-TNF mAbs 1 and 32 on TNF cytotoxicity in WEHI-164 cells.

FuncS

Figure 4 shows the effect of MAb 1 on TNF-induced regression of Meth A solid tumors.

FuncS

Figure 5 shows the effect of MAb 1 and 25 on TNF-induced regression of Meth A ascites tumors.

Publications

Publications (0)

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