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Creative Biolabs

NeuroMab™ Anti-Notch2/3 BBB Shuttle Antibody(NRZP-1022-ZP3236)

[CAT#: NRZP-1022-ZP3236]

Host Species:
Human
Species Reactivity:
Human
Applications:
FC; Inhib; Block; In Vitro; In Vivo; Antagonist

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Immunogen

extracellular domain of a human Notch receptor

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Human

Applications

FC; Inhib; Block; In Vitro; In Vivo; Antagonist

Relevant Diseases

Alzheimer's Disease; Epilepsy; Pain
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

Notch2/3

Official Name

Notch2/3

Alternative Names

NOTCH2; AGS2; HJCYS; hN2; Notch-2; notch 2; notch receptor 2; NOTCH3; CADASIL; CASIL; IMF2; LMNS; CADASIL1; notch 3; notch receptor 3
Publications

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For Research Use Only. Not For Clinical Use.
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