NeuroMab™ Anti-NOTCH3 Antibody(NRP-0422-P1852)
[CAT#: NRP-0422-P1852]
Functional antibody against Human Notch3
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; WB; IHC; FC; Inhib; Agonist; In Vitro; In Vivo
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
NRP-0422-P1852 is an agonistic monoclonal antibody and useful for the treatment of Notch 3 related diseases or disorders.
Immunogen
Notch3 Extracellular Domain-FC Fusion Protein
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
ELISA; WB; IHC; FC; Inhib; Agonist; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease; Epilepsy; Pain
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
NOTCH3
Official Name
NOTCH3
Full Name
Notch 3
Alternative Names
Notch 3; Neurogenic Locus Notch Homolog Protein 3; Notch (Drosophila) Homolog 3; Notch Homolog 3 (Drosophila); Notch Homolog 3; CADASIL1;
Product Pictures
FuncS
Figure 1 depicts a luciferase reporter assay showing activation of the Notch 3 receptor by an anti-Notch 3 monoclonal antibody.
Agonist
Figure 2 depicts the effect of Notch 3 agonistic antibodies on Notch 3 metalloprotease cleavage.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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