NeuroMab™ Anti-NOTCH3 Antibody(NRP-0422-P1853)
Functional antibody against Human Notch3
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; WB; IHC; FC; Inhib; Agonist; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Immunogen
Species Reactivity
Clonality
Host Species
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Target
Official Name
Full Name
Alternative Names
Figure 1 depicts a luciferase reporter assay showing inhibition of the Notch3 ligand Jagged 1 by anti-Notch3 MAbs.
Figure 2 depicts a luciferase reporter assay showing inhibition of the Notch3 ligand Jagged 2 by an anti-Notch3 MAb.
Figure 3 depicts a luciferase reporter assay showing the inhibitory effect of anti-Notch3 MAbs on the Notch3 ligand DLL4.
Figure 4 depicts a luciferase reporter assay showing the inhibitory effect of anti-Notch3 MAbs on native Notch3 in ovarian cancer cells.
Figure 5 depicts an apoptosis assay showing that Jagged1-induced cell survival effects are inhibited by anti-Notch3 MAbs.
Figure 6 depicts the inhibitory effect of anti-Notch3 MAbs on cell migration.
Figure 7 depicts an ELISA using 256A-4 as the detection antibody.
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