Product
NeuroMab™ Anti-PHF Tau (pS396) Antibody, Clone C8.3
[CAT#: NRP-0422-P1743]
Functional antibody against Human, Mouse PHF Tau (pS396)
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; ELISA; Inhib; In Vivo; In Vitro
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The monoclonal antibody specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), useful for their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Mouse
Clone Number
C8.3
Applications
WB; ELISA; Inhib; In Vivo; In Vitro
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
PHF Tau (pS396)
Official Name
PHF Tau (pS396)
Full Name
Paired helical filament-tau
Alternative Names
PHF-Tau; MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Product Pictures
FuncS
Figure 1 HEK293 cells and in vitro vaccination.
FuncS
Figure 2 Depletion of tau for inoculation assay (HEK293).
FuncS
Figure 3: Inoculation experiments with depleted material (HEK293)
FuncS
Figure 4. Hippocampal tau pathology in rTg4510 mice inoculated with immunodeficient rTg4510 material.
FuncS
Figure 5. Hippocampal tangle pathology in vaccinated rTg4510 mice treated with D1.2.
FuncS
Figure 6 Tau removal (HEK293) for inoculation experiments
FuncS
Figure 7 Pathology of hippocampal tangles in rTg4510 mice inoculated with D1.2
FuncS
Figure 8 Quantification of aggregated tau after immunodeficiency reduction
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
