NeuroMab™ Mouse Anti-Human FMRP Monoclonal Antibody (CBP4359)
[CAT#: NAB2101146LS]
Anti-FMRP Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ICC; IHC-P
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The gene encoding Fragile X mental retardation protein 1 (FMRP or FMR1), also known as premature ovarian failure 1 (POF1), contains multiple CGG sequence repeats that are positively correlated with impaired cognitive and reproductive function. FMRP may be involved in mRNA transport and synaptic protein synthesis. The gene that encodes FMRP is located in the X chromosome, and an abnormally large number of CGG repeats (200 - 1000 times) causes Fragile X syndrome due to inadequate amounts of FMRP, leading to severe learning deficiency and mental retardation.
Immunogen
This monoclonal antibody was raised against a recombinant protein isolated from baculovirus expressing mouse FMRP.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP4359
Applications
WB; ICC; IHC-P
Application Notes
WB ( 1.0 - 2.0 µg/mL); IHC-P (5.0-10 µg/mL); ICC (5.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 2311
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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