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Creative Biolabs

Mouse Anti-FMRP Monoclonal Antibody (CBP4299)

[CAT#: NAB210170LS]

Anti-FMRP Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB

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Product Overview

Description

Fragile X mental retardation protein 1 (FMRP) is an RNA binding protein important for normal cognitive development. In fragile X syndrome, abnormal expansion of CGG trinucleotide repeats in FMR1, the gene that encodes FMRP, leads to methylation and silencing of this gene. Altered FMPR expression levels leads to severe learning deficits or mental retardation.

Immunogen

Human recombinant protein fragment: amino acids 36-279

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b, κ

Clone Number

CBP4299

Applications

WB

Application Notes

WB (1.0-5.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

FMRP

Official Name

FMRP

Full Name

Helix Aspersa

Alternative Names

FMRF-like peptide

Gene ID

Uniprot ID

Q06787(Human); P35922(Mouse); Q80WE1(Rat)
Publications

Publications (0)

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