NeuroMab™ Anti-HCN1 cyclic nucleotide-gated channel, Clone N70/28 (CBP8261)

Product Overview

Immunogen

Fusion protein amino acids 778-910 (cytoplasmic C-terminus) of rat HCN1 (also known as potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, accession number Q9JKB0)
Mouse: 96% identity (128/133 amino acids identical)
Human: 90% identity (121/133 amino acids identical)
<50% identity with HCN2, HCN3 and HCN4

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8261

Applications

WB; IHC; IP; ICC

Application Notes

No cross-reactivity against HCN2

Research Areas

Ion channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

HCN1

Official Name

HCN1

Full Name

HCN1

Alternative Names

Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 1; Brain Cyclic Nucleotide-Gated Channel 1; BCNG-1; BCNG1; Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1; Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1; EIEE24; HAC-2;

Uniprot ID

Q9JKB0

Product Pictures

Fig. 1 Adult rat and mouse brain membrane (RBM and MBM, respectively) and transfected cell immunoblot: extracts of RBM, HCN1-KO and -WT MBM and COS-1 cells transfected with GFP-HCN1, GFP-HCN2 or Kv2.1 plasmids and probed with N70/28 (left panel) or K89/34 TC supe (right panel).