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Creative Biolabs

NeuroMab™ Anti-HCN3 cyclic nucleotide-gated channel, Clone N141/28 (CBP8263)

[CAT#: NRP-0422-P162]

Species Reactivity:
Mouse; Rat
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 660-779 (cytoplasmic C-terminus) of mouse HCN3 (also known as potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3, hyperpolarization-activated cation channel 3 and HAC-3, accession number O88705)
Rat: 98% identity (118/120 amino acids identical)
Human: 86% identity (105/121 amino acids identical)
<50% identity with HCN1, HCN2 and HCN4

Species Reactivity

Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8263

Applications

WB; IHC; ICC

Application Notes

No cross-reactivity against other HCN's

Research Areas

Ion channels

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

HCN3

Official Name

HCN3

Full Name

HCN3

Alternative Names

Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 3; Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 3; KIAA1535;

Uniprot ID

O88705
Product Pictures
IB

Fig. 1 Immunoblot versus lysates of total brain from HCN3 knockout (KO) and wild-type (WT) mice probed with N141/28.

IHC

Fig. 2 Adult rat hippocampus immunohistochemistry.

IB

Fig. 3 Adult rat brain membrane immunoblot.

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