NeuroMab™ Anti-Kv1.5 potassium channel BBB Shuttle Antibody, Clone K7/45
[CAT#: NRZP-0423-ZP208]
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC; IP; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-KCNA5 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 542-602 (cytoplasmic C-terminus) of rat Kv1.5 (accession number P19024)
Human: 83% identity (51/61 amino acids)
Mouse=96% identity (59/61 amino acids)
Human: 83% identity (51/61 amino acids)
Mouse=96% identity (59/61 amino acids)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
K7/45
Applications
WB; IHC; IP; ICC
Research Areas
K+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
KCNA5
Official Name
KCNA5
Full Name
Kv1.5 K+ channel
Alternative Names
KCNA5; ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1; potassium voltage-gated channel subfamily A member 5
Uniprot ID
P19024
Product Pictures
IB
Fig. 1 Immunoblot on adult rat brain membrane (RBM) and lysates from Kv1.5-transfected (COS+) and untransfected (COS-) COS cells.
IF
Fig. 2 Immunofluorescence staining transiently Kv1.5-transfected COS cells.
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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