NeuroMab™ Anti-Kv2.1 potassium channel subunit BBB Shuttle Antibody, Clone K89/34
[CAT#: NRZP-0423-ZP213]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; IP; ICC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-KCNB1 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Synthetic peptide amino acids 837-853 (HMLPGGGAHGSTRDQSI, cytoplasmic Cterminus) of rat Kv2.1 (also known as Potassium voltage-gated channel subfamily B member 1, Delayed rectifier potassium channel 1, DRK1, Kcnb1 and Shab, accession number P15387)
Mouse: 100% identity (17/17 amino acids identical)
Human: 88% identity (15/17 amino acids identical, RVLPGGGAHGSTRDQSI)
Mouse: 100% identity (17/17 amino acids identical)
Human: 88% identity (15/17 amino acids identical, RVLPGGGAHGSTRDQSI)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
K89/34
Applications
WB; IHC; IP; ICC
Application Notes
No cross-reactivity against rat Kv2.2
Research Areas
K+ channels
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
KCNB1
Official Name
KCNB1
Full Name
Kv2.1 K+ channel
Alternative Names
KCNB1; DRK1; KV2.1; h-DRK1; EIEE26; potassium voltage-gated channel subfamily B member 1
Uniprot ID
P15387
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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