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Creative Biolabs

NeuroMab™ Anti-Notch3 BBB Shuttle Antibody(NRZP-1022-ZP3221)

[CAT#: NRZP-1022-ZP3221]

Host Species:
Humanized
Species Reactivity:
Human
Applications:
WB; ELISA; FC; Cyt; In Vitro; In Vivo

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Immunogen

human Notch3 NRR region

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Humanized

Applications

WB; ELISA; FC; Cyt; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease; Epilepsy; Pain
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

Notch3

Official Name

NOTCH3

Full Name

Notch 3

Alternative Names

Notch 3; Neurogenic Locus Notch Homolog Protein 3; Notch (Drosophila) Homolog 3; Notch Homolog 3 (Drosophila); Notch Homolog 3; CADASIL1;
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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