Mouse Anti-GLS Monoclonal Antibody (CBP2730)

Name: Mouse Anti-GLS Monoclonal Antibody (CBP2730)
SKU: NAB20101806CR
Rating: 5 (1 reviews)

[CAT#: NAB20101806CR]

Mouse Monoclonal (3A12A1) to GLS

Host Species:: Mouse

Species Reactivity:: Human; Porcine; Mouse; Rat

Applications:: IF; IHC; WB; ELISA

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Request Pricing

Inquiry

Product Overview

Description

GLS belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-, glutamate-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease(PMID:1672808).The glutaminase band in AA/C1 cells is more intense than in HT29 cells, in accordance with measurements of glutaminase activity, and had the same molecular mass of approx. 63 kDa. The bands for both cell lines are clearly different in size from both rat liver glutaminase (58 kDa) and rat kidney glutaminase (65 kDa)(PMID:12408749).

Expression Host

Mammalian cells

Immunogen

KGA/GAC fusion protein Ag24227

Species Reactivity

Human; Porcine; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2730

Applications

IF; IHC; WB; ELISA

Application Notes

IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neurotransmitter

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

GLS

Official Name

GLS

Full Name

Glutaminase

Alternative Names

AAD20; GAC; GLS; GLS1; glutaminase; K glutaminase; KIAA0838; L glutamine amidohydrolase

Gene ID

27165(Human); 216456(Mouse); 192268(Rat)

Uniprot ID

Q9UI32(Human); Q571F8(Mouse); P28492(Rat)

References

1. Dai, W., Xu, L., Yu, X., Zhang, G., Guo, H., Liu, H.,... & Liu, T. (2020). OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism. Journal of hepatology, 72(5), 909-923.

Publications