NeuroMab™ Anti-PlexinA1 BBB Shuttle Antibody(NRZP-1022-ZP2514)
- Host Species:
- Chimeric
- Species Reactivity:
- Human; Mouse
- Applications:
- ELISA; In Vitro; Agonist
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Fig.1 illustrates plots each showing dose-dependent antagonistic activity of a control antibody or anti-PlexinA1 antibody (rabbit IgG) at concentrations of 0 to 100 μg/mL against semaphorin 3A-dependent mouse bone marrow-derived dendritic cell contraction.
Sema3A(+) represents values measured with the addition of 1.6 μg/mL of human semaphorin 3A.
Fig.2 illustrates a plot showing binding responses measured by immobilizing mouse chimeric antibodies hPANL#240-mFc, 359B-2-2-3-6-mFc, PXB693-mFc, PXB727-mFc, and PXB361b-mFc onto Protein G biosensors, and applying human PlexinA1 and mouse PlexinA1 thereto.
Sema3A(+) represents values measured with the addition of 1.6 μg/mL of human semaphorin 3A.
Fig.3 illustrates plots showing semaphorin 3A-like agonistic activities of anti-PlexinA1 antibodies against U87-MG cells.
Sema3A(+) represents values measured with the addition of 1.6 μg/mL of human semaphorin 3A.
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