NeuroMab™ Anti-Plexin A1 Antibody(NRP-0422-P591)
A functional antibody raised against Mouse PlexinA1.
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse
- Applications:
- ELISA; In Vitro; Agonist
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Target
Official Name
Full Name
Alternative Names
Gene ID
Figure 1 is a graph showing the binding activity of an anti-mouse PlexinA1 antibody to mouse PlexinA1.
Sema3A(+) indicates the measured value when 0.8 μg/mL of mouse semaphorin 3A was added, and Sema3A(-) indicates the measured value when mouse semaphorin 3A was not added.
Figure 2 illustrates a graph showing the β-β measured by immobilizing the mouse chimeric antibodies hPANL#240-mFc, 359B-2-2-3-6-mFc, PXB693-mFc, PXB727-mFc, and PXB361b-mFc onto a Protein G biosensor. Plot of the binding reaction and applying human PlexinA1 and mouse PlexinA1 on it.
Sema3A(+) indicates the measured value when 0.8 μg/mL of mouse semaphorin 3A was added, and Sema3A(-) indicates the measured value when mouse semaphorin 3A was not added.
Figure 3 illustrates a graph showing the dose-dependent semaphorin 3A-like agonistic activity of anti-PlexinA1 antibodies on contraction of mouse bone marrow-derived dendritic cells.
Sema3A(+) indicates the measured value when 0.8 μg/mL of mouse semaphorin 3A was added, and Sema3A(-) indicates the measured value when mouse semaphorin 3A was not added.
Figure 4 illustrates a graph showing the binding affinity of agonist antibody mouse chimeras PXB693 and PXB727 to mouse PlexinAl, mouse PleixinA2, and chimeric proteins of mouse PlexinAl and PlexinA2. 1: mouse PlexinA1 sema domain, 2: mouse PlexinA1/A2 sema domain chimera, 3: mouse PlexinA2 sema domain, Control Ab: control antibody, PXB693: mouse chimeric antibody PXB693-mFc, PBX727- mFc: mouse chimeric antibody PXB727.
Sema3A(+) indicates the measured value when 0.8 μg/mL of mouse semaphorin 3A was added, and Sema3A(-) indicates the measured value when mouse semaphorin 3A was not added.
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