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Creative Biolabs

NeuroMab™ Anti-ASIC1, Clone N271/44 (CBP8131)

[CAT#: NRP-0422-P30]

Species Reactivity:
Mouse; Rat
Applications:
WB; IHC; ICC

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Product Overview

Immunogen

Fusion protein amino acids 460-526 (cytoplasmic C-terminus) of mouse ASIC1 (also known as Acidsensing ion channel 1, Neuronal amiloride-sensitive cation channel 2, Brain sodium channel 2, BNaC2 and Accn2, accession number Q6NXK8)
Rat: 98% identity (66/67 amino acids identical)
Human: 97% identity (65/67 amino acids identical)
100% identity between ASIC1a and ASIC1b
<40% identity with ASIC2, ASIC3 or ASIC4

Species Reactivity

Mouse; Rat

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8131

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with ASIC2

Research Areas

Ion channels

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

ASIC1

Official Name

ASIC1

Full Name

ASIC1

Alternative Names

ASIC1; ACCN2; ASIC; BNaC2; Acid sensing ion channel subunit 1

Uniprot ID

Q6NXK8
Product Pictures
IB

Fig. 1 Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged ASIC1, ASIC2 or untagged Kv2.1 plasmid and probed with N271/44 (left) or N86/8 (right) TC supe.

IB

Fig. 2 Immunoblot versus whole brain lysates from adult WT, ASIC1 KO and ASIC2 KO mice probed with N271/44 (left) and N52A/42 (right) TC supe.

IHC

Fig. 3 Adult rat brain immunohistochemistry.

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