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Creative Biolabs

NeuroMab™ Anti-Tau Antibody(NRP-0422-P1736)

[CAT#: NRP-0422-P1736]

Functional antibody against Human, Mouse Tau

Host Species:
Humanized
Species Reactivity:
Human; Mouse
Applications:
IHC; ELISA; In Vitro

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Product Overview

Description

The antibody can be used for the diagnosis of molecular biology and Alzheimer's.

Immunogen

HXPGGG or Tau 151-391/4R.

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Humanized

Applications

IHC; ELISA; In Vitro

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Tau

Official Name

Tau

Full Name

Tau

Alternative Names

CD14

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)
Product Pictures
ELISA

Figure 1: Chimeric and murine DC8E8 and Tau 151-391/4R combinations

ELISA

Figure 2: Humanized and chimeric DC8E8 and Tau 151-391/4R combinations. Antibodies co-expressing assembly-encoded DC8E8 RHA or DC8E8 RHB co-expressed with DC8E8 RKA or DC8E8 RKB were compared to antibody binding of fully aptamer antibodies.

ELISA

Figure 3: Combination of humanized and chimeric DC8E8 and Tau 151-391/4R: the Vk version is (the light is installed on the Chain together with what is).

IHC

Figure 4 Immunohistochemical staining of Alzheimer's disease brain tissue with humanized DC8E8 antibody (IgG1).

IHC

Figure 5 Immunohistochemical staining of FTDP-17 brain (mutated in R406W Tau) using humanized DC8E8 antibody (IgG1).

IHC

Figure 6 Immunohistochemical staining for corticobasal degeneration using humanized DC8E8 antibody (IgG1).

IHC

Figure 7 Immunohistochemical staining of stein-leventhal syndrome using humanized DC8E8 antibody (IgG4).

ELISA

Figure 8 Heat resistance of the candidate derivatized DC8E8 antibody: the purified antibody was heated at the commanded Clock temperature for 10 points, then cooled to 4°C, and then Tau combined ELISA was performed.

Publications

Publications (0)

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