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Creative Biolabs

NeuroMab™ Anti-Tau Antibody(NRP-0422-P2279)

[CAT#: NRP-0422-P2279] Review(5) Q&As(3)

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; ELISA; In Vitro; In Vivo

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Product Overview

Description

NRP-0422-P2279 is a mouse monoclonal antibody that binds to human tau at residues 9-18 in the amino terminus.

Immunogen

9-18

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG

Applications

WB; ELISA; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Tau

Official Name

Tau

Alternative Names

MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
The antibody has shown excellent specificity and sensitivity in our analyses
As part of our ongoing neurodegenerative disease research, we've integrated the antibody into our workflow. The antibody's robust performance in both in vitro and in vivo experiments has been remarkable. Its high affinity for Tau proteins has significantly improved the reliability of our results. We also found that the lot-to-lot consistency is excellent, which saves us time and resources in validation.
user
Excellent
For our studies on Tau pathology
It delivers high-quality, reproducible results across various applications, including Western blotting and ELISA. The antibody binds specifically to Tau without cross-reactivity, which is critical for our precision-focused research.
user
Excellent
We chose the antibody for its reputed specificity and weren't disappointed
It has consistently delivered clear, sharp bands in our Western blots. The antibody's reliability has significantly enhanced the accuracy of our tau-related investigations. It's a reliable product that we intend to continue using in our lab.
user
Excellent
Clear, consistent results
We've also successfully used it in in vitro assays, where it has proven to be a robust and dependable reagent. Its high specificity and sensitivity in Western blot applications have allowed us to detect even low levels of Tau protein with confidence. Highly recommended!
user
Excellent
Our team has had great success using the antibody
The antibody's specificity for Tau has been validated in our lab through rigorous testing. Its consistent performance has been instrumental in advancing our research on tauopathies. The quality and reliability of this antibody are truly commendable.
Q&As
Is this antibody suitable for detecting phosphorylated Tau proteins?
The antibody primarily detects total Tau protein and may not be specific for phosphorylated forms. For specific detection of phosphorylated Tau, it is recommended to use phospho-specific antibodies (e.g., [CAT#: NRZP-0323-ZP213]). However, this antibody can be used in conjunction with phospho-specific antibodies to analyze the overall expression and phosphorylation status of Tau in your samples.
Are there any recommended positive control samples for validating this antibody?
For validating the antibody, we recommend using brain lysates from human, mouse, or rat, particularly those known to express high levels of Tau protein, such as Alzheimer’s disease samples. Additionally, recombinant Tau protein can serve as a positive control to confirm the antibody's specificity and performance in your assays.
What is the recommended dilution for using this antibody in Western blot?
For Western blot applications, the recommended dilution of the antibody is 1:1,000 to 1:5,000. Optimal dilution should be determined by the end-user based on the specific experimental conditions. It's advisable to perform a titration experiment to establish the ideal concentration for your specific samples and detection system.
For Research Use Only. Not For Clinical Use.
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