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Creative Biolabs

NeuroMab™ Anti-Tau40 Antibody(NRP-0422-P1677)

[CAT#: NRP-0422-P1677]

Functional antibody against Human Tau40

Host Species:
Chimeric
Species Reactivity:
Human
Applications:
WB; ELISA; In Vitro; In Vivo

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Product Overview

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Chimeric

Applications

WB; ELISA; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Tau40

Official Name

Tau40

Alternative Names

MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)
Product Pictures
IHC

Figure 1 NI-105.4E4 binds neurofibrillary tangles and expresses human TauP301L (NFT), dystrophic neural processes, and neurofibrillary cords in AD mouse brains.

ELISA

Figure 2 Human IgG levels in plasma after intraperitoneal administration of 30 mg/kg NI-105.4E4 or NI-105.4A3 human anti-tau antibody in mice.

ELISA

Figure 3 30 mg/kg NI-105.4E4 or NI-105.4A3 human anti-tau antibody was applied to the human IgG level in mouse retroperitoneal brain homogenate.

ELISA

Figure 4 ELISA measurement of NI-105.40E8 hIgG1 and NI-105.40E8 (R104W) hIgG1.

FuncS

Figure 5 Pathological aggregation of Tau protein in vivo and in brains of AD and tauopathies transgenic mice.

FuncS

Figure 6 Penetration of NI-105.6C5 or NI-105.6E3 anti-tau antibody in the brain of TauP301L mice.

Publications

Publications (0)

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