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Creative Biolabs

NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P804)

[CAT#: NRP-0422-P804] Review(4) Q&As(3)

A functional antibody raised against Human, Mouse TREM2.

Host Species:
Mouse
Species Reactivity:
Human; Mouse
Applications:
FC; ELISA; Block; Inhib; In Vitro; In Vivo; Agonist

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Product Overview

Description

The antibody specifically binds to a human triggering receptor expressed on myeloid cells 2 (TREM2) and useful in preventing, reducing risk, or treating an individual in need.

Immunogen

Mouse Fc Fused Human TREM2 ECD

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Applications

FC; ELISA; Block; Inhib; In Vitro; In Vivo; Agonist

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

TREM2

Official Name

TREM2

Full Name

Triggering receptor expressed on myeloid cells 2

Alternative Names

TREM2; Triggering receptor expressed on myeloid cells 2

Gene ID

54209(Human)

Uniprot ID

Q9NZC2(Human)
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
I have used the antibody for several in vitro assays, and the results have been consistently reliable
The antibody has high specificity and affinity, which has greatly improved the accuracy of my ELISA experiments. Additionally, its performance in flow cytometry is exceptional, providing clear and distinct populations.
user
Excellent
I highly recommend this product for anyone studying TREM2-related pathways
We've used it in both in vitro and in vivo studies, and the results have been outstanding. The antibody's blocking and inhibiting capabilities have provided us with crucial insights into TREM2's role in microglial activation.
user
Excellent
I've used the antibody for flow cytometry and ELISA assays
I am very pleased with its performance. The antibody shows excellent specificity, and the signal-to-noise ratio is impressive. It has helped us identify TREM2 expression in different cell populations with high precision.
user
Excellent
We have had great success in our experiments
The antibody's ability to inhibit TREM2 function in vitro has been particularly useful in our studies of neuroinflammation. It has also worked well in blocking assays, providing consistent and reproducible results. I highly recommend this antibody.
Q&As
Can the antibody be used in conjunction with other antibodies for double labeling experiments?
Yes, the antibody can be used for double labeling experiments. It is important to ensure that the secondary antibodies used are species-specific to avoid cross-reactivity. Proper optimization and validation of the double labeling protocol are crucial to obtain clear and specific results when using multiple antibodies in the same assay.
What is the concentration of the antibody provided in the vial?
The antibody is typically provided at a concentration of 1 mg/mL. This high concentration allows for multiple experiments and dilutions according to the requirements of different applications. Detailed concentration and storage instructions are provided with the product to ensure optimal use.
Is there any support available if I encounter issues?
Yes, comprehensive support is available for users of the antibody. Our technical support team is ready to assist with any issues or questions regarding the antibody’s use, optimization, and troubleshooting. You can contact our support team via email or phone, and we also provide detailed protocols and troubleshooting guides to help you achieve the best results in your experiments.
For Research Use Only. Not For Clinical Use.
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