NeuroMab™ Anti-TREM2 Antibody(NRP-0422-P789)

Product Overview

Description

The anti-TREM2 antibody can be used for enhancing an immune response and/or for the treatment of an immune-related condition in an individual.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

FC; IHC; Cyt; ADCP; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

TREM2

Official Name

TREM2

Full Name

Triggering receptor expressed on myeloid cells 2

Alternative Names

TREM2; Triggering receptor expressed on myeloid cells 2

Gene ID

54209(Human)

Uniprot ID

Q9NZC2(Human)

Product Pictures

Cyt

Figure 1 shows that anti-Trem2 mAb clone 7 induces ADCP of target cells by bone marrow-derived macrophages.

ELISA

Figure 2 shows the binding characteristics of anti-TREM2 antibodies (Pil.2 Clone 2, Pil.2, Clone 5, and Pil.2 Clone 7). Absolute absorbance is plotted on the Y-axis, phage clones not displaying Fab are shown as controls for non-specific binding (K07.)

Publications