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Creative Biolabs

Mouse Anti-TLE1 Monoclonal Antibody (CBP2717)

[CAT#: NAB20101793CR]

Mouse Monoclonal (2F2H11) to TLE1

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC; WB; ELISA

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Product Overview

Description

Transducin-like enhancer protein 1(TLE1) is a transcriptional corepressor. It can bind to and regress expression of many transcription factors such as NFkB, which is mediated by FOXA2, CTNNB1 and TCF family member in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Expression of TLE1 is highest in skeletal muscle and liver, moderate in placenta, heart, kidney, and spleen, and weak in all other tissues including brain.

Expression Host

Mammalian cells

Immunogen

TLE1 fusion protein Ag21327

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2717

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

GPCR

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1047 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

TLE1

Official Name

TLE1

Full Name

Transducin-like enhancer of split 1

Alternative Names

E(Sp1) homolog; ESG; ESG1; GRG1; TLE1

Gene ID

7088(Human); 21885(Mouse); 362533(Rat)

Uniprot ID

Q04724(Human); Q62440(Mouse)
Publications

Publications (0)

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