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Creative Biolabs

Mouse Anti-CNP Monoclonal Antibody (CBP6791)

[CAT#: NAB2007FY1740]

Oligodendrocytes

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
IHC; WB

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Product Overview

Description

Neuroinflammation is locally produced in the central nervous system through phenotypic changes of different non-neuronal cell types (such as microglia, oligodendrocytes, and astrocytes) in the brain, leading to different cytokines and chemokines The release of C, eventually recruits and infiltrates peripheral blood cells, mainly T-and B cells, into the brain parenchyma. 2', 3'-cyclic nucleotide 3'-phosphodiesterase, also known as CNPase, is an enzyme encoded by the CNP gene in humans.

CNPase is an enzyme associated with myelin, which accounts for 4% of the total CNS myelin protein, and is believed to undergo major age-related changes. It is named for its ability to catalyze the hydrolysis of 2', 3'-cyclic nucleotide phosphodiester to 2'-nucleotides, although the internal understanding of its specific physiological function remains unclear.

Epitope

Binds to an located within the peptide sequence PGVLHCTTKFCDYGK

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP6791

Applications

IHC; WB

Application Notes

IHC: 1:2500-1:5000
WB: 1 µg/ml

Marker

Glial Cell Markers; Oligodendrocyte Markers
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

0.7 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

Myelin CNPase

Official Name

CNP

Full Name

CNPase

Alternative Names

CNP; CNP1; 2'; 3'-cyclic nucleotide 3' phosphodiesterase; CNPase

Gene ID

1267 (Human); 12799 (Mouse); 25275 (Rat)

Uniprot ID

P09543 (Human); P16330 (Mouse); P13233 (Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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