NeuroMab™ Anti-Galanin BBB Shuttle Antibody(NRZP-1022-ZP3375)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; FC; Inhib; Block; Cyt; In Vitro
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 shows the results of the GALR2 filtration assay.
Membrane preparations from A9 cells engineered to overexpress GALR2 were incubated with 125I-labeled human galanin and mouse anti-galanin hybridoma supernatants and harvested onto GF/B Unifilter plates. Twenty-one hybridomas were able to inhibit the binding of human galanin to GALR2.
Figure 2 shows the results of the affinity assay.
Figure 3 shows that administration of anti-galanin antibodies reduces tumor growth in established tumors.
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