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Creative Biolabs
Product

NeuroMab™ Anti-SORT1 BBB Shuttle Antibody,Clone NR3312P

[CAT#: NRZP-1022-ZP3963]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
In Vitro; In Vivo; Inhib; ELISA; Block

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

NR3312P

Applications

In Vitro; In Vivo; Inhib; ELISA; Block

Relevant Diseases

Parkinson's Disease
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

SORT1

Official Name

SORT1

Full Name

Sortilin

Alternative Names

SORT1; Gp95; LDLCQ6; NT3; NTR3; Sortilin 1
Product Pictures
ELISA

Figure 1 Evaluation of extracellular PGRN levels in media from sortin-overexpressing HEK cell cultures by ELISA (S18).

Figure 2 shows representative peptides covering the 45, 68 and 811 conformational epitopes of antibodies.

Figure 3 shows representative peptides covering the 45, 68 and 811 conformational epitopes of antibodies.

Figure 4 shows representative peptides covering the 45, 68 and 811 conformational epitopes of antibodies.

Figure 5 shows representative peptides covering the conformational epitopes of antibodies 45, 68 and 811.

Figure 6 shows representative peptides covering the 45, 68 and 811 conformational epitopes.

Figure 7 shows representative peptides covering the 45, 68 and 811 conformational epitopes of antibodies.

Figure 8 shows representative peptides covering the 45, 68 and 811 conformational epitopes.

Figure 9 shows representative peptides covering the 45, 68 and 811 conformational epitopes.

Figure 10 shows representative peptides covering the 45, 68 and 811 conformational epitopes of antibodies.

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For Research Use Only. Not For Clinical Use.
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