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Creative Biolabs

NeuroMab™ Anti-CD146 BBB Shuttle Antibody(NRZP-1222-ZP1126)

[CAT#: NRZP-1222-ZP1126]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
Inhib; Block; In Vitro

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Product Overview

Description

CD146 is an adhesion molecule that plays important roles in angiogenesis, cancer metastasis, and immune response. It exists as a monomer or dimer on the cell surface. NRZP-1222-ZP1126 is a monoclonal antibody that binds to CD146, which abrogates the activation of CD146-mediated signaling pathways and shows inhibitory effects on tumor growth.

Species Reactivity

Human

Host Species

Mouse

Applications

Inhib; Block; In Vitro

Relevant Diseases

Multiple Sclerosis
Target

Target

CD146

Official Name

MCAM

Full Name

Cluster of differentiation 146

Alternative Names

MCAM; CD146; MUC18; melanoma cell adhesion molecule; HEMETCAM; MelCAM
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