Neural Marker Antibodies
Neurons are the primary structural and functional components of the nervous system, featuring four distinct morphological components: the cell body (soma), dendrites, an axon, and presynaptic terminals. The soma is the core of cell metabolism and contains the nucleus and other organelles containing the cell's DNA. Dendrites are receivers of incoming signals. Axons generate outgoing signals. Presynaptic terminals, which contain vesicles containing neurotransmitters, are found at the ends of each axon branch. Neuronal cells are highly polarized and collect information from upstream neurons or the environment via dendritic branches, while axons send integrated information to downstream neurons or non-neuronal cells (such as muscles) via synapses.
Studying nerve cells with various functions is a vital first step in understanding how the neurological system operates. Researchers can easily identify neurons with distinct roles using antibodies targeting these neuronal markers. Additionally, researchers can:
- Examine the morphology and phenotype of neurons
- Evaluating co-localization of proteins
- Displaying synaptic connections visually
- Quantify the expression of proteins
- Determine the state of cell development
Markers of Neural Structure
Creative Biolabs provides antibodies against markers that are expressed precisely in each structural unit of neurons.
Structural Unit | Markers |
Nuclear Markers | c-Fos , FUS , HDAC1 , HDAC2 , HDAC3 , HDAC8 , NeuN , MECP2 , PCNA , STAT3 |
Soma Markers | NSE , Tyrosine Hydroxylase |
Dendrite Markers | MAP2 |
Axon Markers | Neurofilament L , Neurofilament M , Neurofilament M/H , Neurofilament H , Pan-Neurofilament, Tau |
Axon, Dendrite, and Soma Markers | α-Tubulin , β-Actin , β3-Tubulin |
Presynaptic Markers | Ankyrin-B , Cask , GRK , Snap-25 , Stonin-2 , SVOP , Synapsin , Synaptobrevin (VAMP) , Synaptophysin , Synaptotagmin-3 , Synaptotagmin-6 , Synaptotagmin-12 , Syntaxin , VGlut1 , VGlut2 , Wave1 |
Postsynaptic Markers | ADAM22 , ASIC1 , IP3R1 , Maguk , Neurogranin , PSD93 , PSD95 , SAP102 , SAP97 , SAPAP , Shank , SynDIG1 , Thorase |
Myelin Sheath Markers | Myelin Basic Protein , Myelin CNPase |
Summary of Various Neuronal Markers
We also offer reliable labeling antibodies for different kinds and stages of neurons.
Neuron Types | Markers |
Neuroepithelial cells | Nestin , SOX2 , notch1 , HES1 , HES3, E-Cadherin , occludin |
Immature neurons | Doublecortin , β3-Tubulin , NeuroD1 , TBR1 , stathmin 1 , DCX |
Mature neurons | NeuN , MAP2 , 160kDa neurofilament medium , 200kDa neurofilament heavy , synaptophysin , PSD95 |
Glutamatergic neurons | vGluT1 , vGluT2 , NMDAR1 , NMDAR2B , Glutaminase , Glutamine synthetase |
GABAergic neurons | GABA transporter 1 , GABAB receptor 1 , GABAB receptor 2 , GAD65 , GAD67 |
Dopaminergic neurons | Tyrosine Hydroxylase , Dopamine Transporter , FOXA2 , GIRK2 , Nurr1 , LMX1B |
Serotonergic neurons | Tryptophan Hydroxylase , Serotonin Transporter , Pet1 |
Cholinergic neurons | Choline Acetyltransferase , Acetylcholine Transporter , Acetylcholinesterase |
Additional Neuronal Markers | Polysialic acid-neural cell adhesion molecule (PSA-NCAM) , Neurogenic Differentiation 1 (NeuroD or Beta2) , Calbindin-D28k , Calretinin , Synaptoporin (SYNPR, SPO) |
Glial Cell Markers
Aside from the neurons that make up the central or peripheral nervous system, there is another type of non-neuronal cell called glial cells that offer structural and metabolic support to neurons. Glial cells consist of:
- NeuroMab™ Mouse Anti-EFNB2 Monoclonal Antibody (CBP1159) (Cat#: NAB-0720-Z4396)
- NeuroMab™ Anti-TNFα BBB Shuttle Antibody(NRZP-1022-ZP4105) (Cat#: NRZP-1022-ZP4105)
- NeuroMab™ Anti-PVRIG Antibody(NRP-0422-P515) (Cat#: NRP-0422-P515)
- Tau Monoclonal Antibody (AT120, HT7 and BT2 clone) (Cat#: NK-2106-P008)
- NeuroMab™ Rabbit Anti-LRRK2 Monoclonal Antibody (CBP1887) (Cat#: NAB-08-PZ735)
- NeuroMab™ Mouse Anti-LRP1 Monoclonal Antibody (CBP3363) (Cat#: NAB-0720-Z6479)
- NeuroMab™ Anti-Alpha Synuclein BBB Shuttle Antibody(NRZP-1022-ZP4050) (Cat#: NRZP-1022-ZP4050)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1686) (Cat#: NRP-0422-P1686)
- NeuroMab™ Anti-PVRIG Antibody(NRP-0422-P1803) (Cat#: NRP-0422-P1803)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2293) (Cat#: NRP-0422-P2293)
- Human Hippocampal Neuron Cells HPPNCs (Cat#: NCL2110P106)
- Mouse Midbrain Dopaminergic Neuron Cell MN9D (Cat#: NCL2110P059)
- Mouse Retinal Ganglion Cell Line RGC-5 (Cat#: NCL2110P154)
- iNeu™ Microglia (Cat#: NCL-7P018)
- Rat Retinal Muller Cell Line, Immortalized (Cat#: NCL-21P6-192)
- Mouse Retinal Ganglion Cells (Cat#: NCL2110P145)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
- iNeu™ Retinal Pigment Epithelial Cells (RPE) (Cat#: NRZP-0323-ZP92)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
- Mouse Glioma Cell Line GL261 (Cat#: NCL-2108P28)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Beta Amyloid (1-40), Aggregation Kit, TTF Assay (Cat#: NRZP-0323-ZP199)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
- pAAV-EF1a-DIO-EGFP-WPRE (Cat#: NTA-2012AD-P285)
- PRV-CAG-EGFP (Cat#: NTA-2011-ZP14)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- AAV-mDLX-CRE-tdTomato (Cat#: NRZP-0622-ZP721)
- AAV2/2Retro-CAG-DIO-EGFP-2A-TetTox-pA [Neural Tracing] (Cat#: NTA-2012-ZP303)
- Dextran, NHS Activated, 40 kDa (Cat#: NRZP-0722-ZP124)
- pAAV-syn-jGCaMP8f-WPRE (Cat#: NTA-2106-P061)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- AAV2 Full Capsids, Reference Standards (Cat#: NTC2101070CR)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- ABCA1 Antisense Oligonucleotide (NV-2106-P27) (Cat#: NV-2106-P27)
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Human huntingtin (HTT) (NM_002111) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0497)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP501)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-TNFR BBB Shuttle Protein (Cat#: NRZP-0423-ZP510)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)