Oligodendrocyte Marker Related Research Reagents
Oligodendrocytes (ODs) are glial cells in the central nervous system (CNS) that form the myelin sheath of axons to support rapid nerve conduction. OD also contributes to neuroplasticity and provides nutritional support for neurons. Each OD can interact with multiple axons and has the ability to quickly update its myelin sheath. Each myelin sheath of oligodendrocytes has up to 50 independent axons. As a result, OD has a high metabolic rate and is very susceptible to oxidative stress. OD is highly sensitive to pro-inflammatory molecules produced during inflammation and responds by producing low-quality myelin. In addition, OD can also affect neuronal survival, axon transport, axon caliber, and ion channel aggregation along the axon. OD damage and dysfunction are responsible for the development of many diseases and conditions, including multiple sclerosis, schizophrenia, and bipolar disorder.
Each stage of oligodendrocyte differentiation and maturation can be monitored by the specific morphology markers, including the most common maturation stage markers CNPase, Olig2 and oligodendrocyte marker O4. Creative Biolabs provides a series of research tools needed to study the development, maturation and function of oligodendrocytes. Our product portfolio includes monoclonal antibodies, polyclonal antibodies, labeled antibodies, proteins, analytical kits, and small molecule activators and inhibitors.
Summary of Oligodendrocyte Markers Provided by Creative Biolabs
Oligodendrocyte Precursor Cell Markers
| Subcellular Localization | Markers | |
| Nuclear |
NKX2.2 Olig2 |
SOX10 |
| Cytoplasmic | Olig2 | |
| Cell Surface |
A2B5 NG2/MCSP |
Oligodendrocyte Marker O4 PDGF Rα |
Immature Oligodendrocyte Markers
| Subcellular Localization | Markers | |
| Cytoplasmic | CNPase | |
| Cell Surface | Oligodendrocyte Marker O1 | Oligodendrocyte Marker O4 |
Non-Myelinating Oligodendrocyte Markers
| Subcellular Localization | Markers | |
| Cytoplasmic |
CNPase Nogo-A |
APC |
| Cell Surface |
Oligodendrocyte Marker O1 Myelin PLP |
Oligodendrocyte Marker O4 |
Myelinating Oligodendrocyte Markers
| Subcellular Localization | Markers | |
| Cytoplasmic |
CNPase TPPP/p25 MBP |
APC OMgp Nogo-A |
| Cell Surface |
Caspr2 MAG/Siglec-4a |
MOG Myelin PLP |
For Research Use Only. Not For Clinical Use.
Target
Related Products
Loading...
Mouse Anti-CSPG4 Monoclonal Antibody (CBP7066) [CAT#: NAB-0720-Z9090]
NG2 Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FCM
- Conjugation:
- Unconjugated
Mouse Anti-CNP Monoclonal Antibody (CBP7065) [CAT#: NAB-0720-Z9089]
CNPase Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P
- Conjugation:
- Unconjugated
Rabbit Anti-CNP Monoclonal Antibody (CBP7064) [CAT#: NAB-0720-Z9080]
CNPase Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB
- Conjugation:
- Unconjugated
Rabbit Anti-CLDN11 Monoclonal Antibody (CBP7063) [CAT#: NAB-0720-Z9057]
Oligodendrocyte Specific Protein Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- FCM; WB
- Conjugation:
- Unconjugated
Rabbit Anti-SMPD2 Monoclonal Antibody (CBP7062) [CAT#: NAB-0720-Z9055]
nSMase Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IP
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-MBP Monoclonal Antibody (CBP7061) [CAT#: NAB-0720-Z9049]
Myelin Basic Protein Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P; Protein Array
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-PMP22 Monoclonal Antibody (CBP7060) [CAT#: NAB-0720-Z9045]
PMP22 Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- IMC™; WB; IHC-P; IHC-Fr
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-CNTNAP1 Monoclonal Antibody (CBP7059) [CAT#: NAB-0720-Z9044]
Caspr Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- IMC™; WB; IHC-P; IHC-Fr
- Conjugation:
- Unconjugated
iNeuMab™ Mouse Anti-CNTNAP1 Monoclonal Antibody (CBP7058) [CAT#: NAB-0720-Z9041]
Caspr2/CNTNAP2 Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-MBP Monoclonal Antibody (CBP7057) [CAT#: NAB-0720-Z9038]
Myelin Basic Protein Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB
- Conjugation:
- Unconjugated
Mouse Anti-PLP Monoclonal Antibody (CBP7056) [CAT#: NAB-0720-Z9037]
Myelin PLP Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Cow
- Applications:
- IHC-Fr; WB; ICC; IF; IHC
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-MBP Monoclonal Antibody (CBP7055) [CAT#: NAB-0720-Z9034]
Myelin Basic Protein Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- WB; IHC-P
- Conjugation:
- Unconjugated
Mouse Anti-APC Monoclonal Antibody (CBP7054) [CAT#: NAB-0720-Z9032]
APC Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Rat; Human; Monkey
- Applications:
- FCM; IHC-P; ICC; IF; IHC-Fr
- Conjugation:
- APC
iNeuMab™ Rabbit Anti-PLP Monoclonal Antibody (CBP7053) [CAT#: NAB-0720-Z9031]
Myelin PLP Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- IHC-P; IP
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-CNTNAP1 Monoclonal Antibody (CBP7052) [CAT#: NAB-0720-Z9030]
Caspr2/CNTNAP2 Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IHC-P
- Conjugation:
- Unconjugated
Mouse Anti-CNTNAP1 Monoclonal Antibody (CBP7051) [CAT#: NAB-0720-Z9026]
Caspr Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IHC-P; ICC; IF
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-PMP22 Monoclonal Antibody (CBP7050) [CAT#: NAB-0720-Z9024]
PMP22 Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- WB; IHC-P; ICC; IF; IP; FCM
- Conjugation:
- Unconjugated
Mouse Anti-MBP Monoclonal Antibody (CBP7049) [CAT#: NAB-0720-Z9022]
Myelin Basic Protein Mouse Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Rat; Sheep; Rabbit; Goat; Human
- Applications:
- WB; ELISA; IHC-P; IHC-Fr; ICC; IF; FCM; IHC-Fr
- Conjugation:
- Unconjugated
iNeuMab™ Rabbit Anti-APC Monoclonal Antibody (CBP7048) [CAT#: NAB-0720-Z9020]
APC Rabbit Monoclonal Antibody
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IHC-P; IP; FCM; ICC
- Conjugation:
- Unconjugated
Human Anti-MBP Monoclonal Antibody (CBP7047) [CAT#: NAB-0720-Z9019]
Myelin Basic Protein Human Monoclonal Antibody
- Host Species:
- Human
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- ELISA; WB; ICC; IF; IHC-P
- Conjugation:
- Unconjugated
Mouse Anti-CNP Monoclonal Antibody (CBP6793) [CAT#: NAB2007FY1742]
Oligodendrocytes
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB; IF
Mouse Anti-CNP Monoclonal Antibody (CBP6792) [CAT#: NAB2007FY1741]
Oligodendrocytes
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
Mouse Anti-CNP Monoclonal Antibody (CBP6791) [CAT#: NAB2007FY1740]
Oligodendrocytes
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
Mouse Anti-MOG Monoclonal Antibody (CBP6790) [CAT#: NAB2007FY1739]
Oligodendrocytes
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
Mouse Anti-MOG Monoclonal Antibody (CBP6789) [CAT#: NAB2007FY1738]
Oligodendrocytes
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- IHC; WB
Human Glypican 1 (GPC1) Antibody Pair, BSA and Azide Free [Colorimetric] [CAT#: NPP2011ZP67]
- Applications:
- ELISA
Human CSPG4 Antibody Pair, BSA and Azide Free [Colorimetric/Fluorometric] [CAT#: NPP2011ZP66]
- Applications:
- ELISA
iNeuMab™ Mouse Anti-Human NRG1 Monoclonal Antibody (CBP1916) [CAT#: NAB-08-PZ915]
Mouse Monoclonal Antibody to NRG1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
iNeuMab™ Rabbit Anti-Human CSPG4 Monoclonal Antibody (CBP1911) [CAT#: NAB-08-PZ882]
Rabbit Monoclonal Antibody to NG2
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- WB; ICC; IF; IHC-P
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
iNeuMab™ Rabbit Anti-MBP Monoclonal Antibody (CBP1900) [CAT#: NAB-08-PZ797]
Rabbit Monoclonal Antibody to Myelin Basic Protein
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse; Rat; Human
- Applications:
- WB; IHC-P; IHC-Fr
- Conjugation:
- Unconjugated; APC; PE; HRP; Biotin; FITC
Product
Hot Products
Antibodies
- NeuroMab™ Anti-ApoC3 BBB Shuttle Antibody(NRZP-1022-ZP3503) (Cat#: NRZP-1022-ZP3503)
- NeuroMab™ Anti-CD32b Antibody(NRP-0422-P1803) (Cat#: NRP-0422-P1803)
- NeuroMab™ Anti-Alpha Synuclein Antibody(NRP-0422-P614) (Cat#: NRP-0422-P614)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1684) (Cat#: NRP-0422-P1684)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P1683) (Cat#: NRP-0422-P1683)
- NeuroMab™ Anti-TREM2 BBB Shuttle Antibody(NRZP-1022-ZP4114) (Cat#: NRZP-1022-ZP4114)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2275) (Cat#: NRP-0422-P2275)
- NeuroMab™ Anti-Integrin αvβ8 BBB Shuttle Antibody(NRZP-1222-ZP1218) (Cat#: NRZP-1222-ZP1218)
- NeuroMab™ Anti-Tau Antibody(NRP-0422-P2293) (Cat#: NRP-0422-P2293)
- Mouse Anti-Human α-Synuclein Phospho (Tyr39) (CBP3706) (Cat#: NAB201250LS)
More
Cells
- Rat Glioma Cell Line C6 (Cat#: NCL2110P346)
- Human Brain Astroblastoma U-87 MG (Cat#: NCL2110P117)
- iNeu™ Human Motor Neurons (Cat#: NCL-2103-P71)
- Mouse Microglia Cell Line BV-2, Immortalized (Cat#: NCL2110P153)
- Mouse Glioma Cell Line GL261 (Cat#: NCL-2108P28)
- Rat Muller Cell (Cat#: NCL2110P040)
- Rat Schwann Cells RSC96, Immortalized (Cat#: NCL-2108P21)
- Rat Immortalized Retinal Muller Cell Line rMC-1 (Cat#: NCL-2106-S93)
- Human Brain Microvascular Endothelial Cells (Cat#: NCL-2103-P133)
- Human Microglia Cell Line HMC3, Immortalized (Cat#: NCL-2108P38)
More
Kits
- Alpha Synuclein Aggregation Kit (Cat#: NRZP-1122-ZP15)
- Beta Amyloid (1-40), Aggregation Kit (Cat#: NRZP-0323-ZP199)
- Amyloid beta 1-42 Kit (Cat#: NRP-0322-P2170)
- Beta Amyloid (1-42), Aggregation Kit (Cat#: NRZP-0323-ZP200)
- Human GFAP ELISA Kit [Colorimetric] (Cat#: NPP2011ZP383)
- Human Poly ADP ribose polymerase,PARP Assay Kit (Cat#: NRZP-1122-ZP62)
- Human Tau Aggregation Kit (Cat#: NRP-0322-P2173)
- Alpha-Synuclein Aggregation Assay Kit (Cat#: NRZP-1122-ZP37)
More
Tracers
- AAV2/9-hEF1a-fDIO-eNpHR 3.0-mCherry-WPRE-pA (Cat#: NTA-2012-ZP78)
- Dextran-FITC (Cat#: NTA-2011-ZP110)
- VSV-eGFP (Cat#: NTA-2011-ZP20)
- Dextran, Cy5 Labeled, 2000 kDa (Cat#: NRZP-0722-ZP22)
- pAAV-syn-FLEX-jGCaMP8m-WPRE (Cat#: NTA-2106-P065)
- pAAV-syn-FLEX-jGCaMP8f-WPRE (Cat#: NTA-2106-P064)
- Dextran, NHS Activated, 40 kDa (Cat#: NRZP-0722-ZP124)
- pAAV-syn-FLEX-jGCaMP8s-WPRE (Cat#: NTA-2106-P066)
- rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA (Cat#: NTA-2010-TT342)
- pAAV-syn-jGCaMP8m-WPRE (Cat#: NTA-2106-P062)
More
Gene Related Products
- Tau Antisense Oligonucleotide (IONIS-MAPTRx) (Cat#: NV-2106-P29)
- Human apolipoprotein E (APOE) (NM_000041) ORF clone, Untagged (Cat#: NEP-0421-R0232)
- App Rat amyloid beta (A4) precursor protein (App)(NM_019288) ORF clone, Untagged (Cat#: NEP-0421-R0053)
- Rat Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2) (NM_020093) ORF clone/lentiviral particle, Myc-DDK Tagged (Cat#: NEP-0621-R0041)
- Human superoxide dismutase 1, soluble (SOD1) (NM_000454) ORF clone, TurboGFP Tagged (Cat#: NEP-0521-R0748)
- Lenti of Human TAR DNA binding protein (TARDBP) (NM_007375) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0832)
- Human presenilin 1 (PSEN1), transcript variant 2 (NM_007318) ORF clone, TurboGFP Tagged (Cat#: NEP-0421-R0140)
- Human superoxide dismutase 3, extracellular (SOD3) (NM_003102) ORF clone, Untagged (Cat#: NEP-0521-R0808)
- Lenti of Mouse synuclein, alpha (Snca) transcript variant (NM_001042451) ORF clone, mGFP Tagged (Cat#: NEP-0521-R0864)
- Human huntingtin-associated protein 1 (HAP1) transcript variant 2 (NM_177977) ORF clone, Myc-DDK Tagged (Cat#: NEP-0521-R0676)
More
Biospecimens
- NeuroBiologics™ Mouse Cerebrospinal Fluid (Cat#: NRZP-0822-ZP497)
- NeuroBiologics™ Monkey Cerebrospinal Fluid (Cat#: NRZP-0822-ZP495)
- NeuroBiologics™ Rat Cerebrospinal Fluid (Cat#: NRZP-0822-ZP496)
- NeuroBiologics™ Pig Cerebrospinal Fluid (Cat#: NRZP-0822-ZP498)
- NeuroBiologics™ Human Cerebrospinal Fluid (Cat#: NRZP-0822-ZP491)
More
Cell Assay Reagents
- NeuroPro™ Anti-SGSH BBB Shuttle Protein (Cat#: NRZP-0423-ZP505)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP509)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP498)
- NeuroPro™ Anti-ASA BBB Shuttle Protein (Cat#: NRZP-0423-ZP504)
- NeuroPro™ Anti-IDS BBB Shuttle Protein (Cat#: NRZP-0423-ZP503)
- NeuroPro™ Anti-EPO BBB Shuttle Protein (Cat#: NRZP-0423-ZP508)
- NeuroPro™ Anti-IDUA BBB Shuttle Protein (Cat#: NRZP-0423-ZP502)
- NeuroPro™ Anti-GDNF BBB Shuttle Protein (Cat#: NRZP-0423-ZP500)
- NeuroPro™ Anti-idursulfase BBB Shuttle Protein (Cat#: NRZP-0423-ZP497)
- NeuroPro™ Anti-NAGLU BBB Shuttle Protein (Cat#: NRZP-0423-ZP506)
More
