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![](static/images/product/product-icon-neural-antibodies.png)
NeuroMab™ Anti-Plexin A1 Antibody,Clone NR3623P
A functional antibody raised against Mouse PlexinA1.
- Host Species:
- Rabbit
- Species Reactivity:
- Mouse
- Applications:
- ELISA; In Vitro; Agonist
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Target
Official Name
Full Name
Alternative Names
Gene ID
Figure 1 is a graph showing the binding activity of an anti-mouse PlexinA1 antibody to mouse PlexinA1.
The X-axis represents the antibody concentration, and the Y-axis represents the absorbance at a wavelength of 405 nm. Solid lines indicate binding to Ba/F3 cell line expressing high levels of mouse PlexinA1, dashed lines indicate binding to Ba/F3 cells.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P510-1.png)
Figure 2 is a graph showing the dose-dependent antagonistic activity of a control antibody or an anti-PlexinA1 antibody (rabbit IgG) at a concentration of 0 to 100 µg/mL on the contraction of semaphorin 3A-dependent mouse bone marrow-derived dendritic cells.
Sema3A(+) indicates the measured value when 0.8 μg/mL of mouse semaphorin 3A was added, and Sema3A(-) indicates the measured value when mouse semaphorin 3A was not added.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P510-2.png)
Figure 3 illustrates a graph showing the β-β measured by immobilizing the mouse chimeric antibodies hPANL#240-mFc, 359B-2-2-3-6-mFc, PXB693-mFc, PXB727-mFc, and PXB361b-mFc onto a Protein G biosensor. Plot of the binding reaction and applying human PlexinA1 and mouse PlexinA1 on it.
Sema3A(+) indicates the measured value when 0.8 μg/mL of mouse semaphorin 3A was added, and Sema3A(-) indicates the measured value when mouse semaphorin 3A was not added.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P510-3.png)
Figure 4 illustrates a graph showing the binding affinity of the antagonist antibody mouse chimera PXB361b to mouse PlexinAl, mouse PleixinA2, and chimeric proteins of mouse PlexinAl and PlexinA2. 1: mouse PlexinA1 sema domain, 2: mouse PlexinA1/A2 sema domain chimera, 3: mouse PlexinA2 sema domain, Control Ab: control antibody, PXB361b: mouse chimeric antibody PXB361b-mFc.
Sema3A(+) indicates the measured value when 0.8 μg/mL of mouse semaphorin 3A was added, and Sema3A(-) indicates the measured value when mouse semaphorin 3A was not added.
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P510-4.png)
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