NeuroMab™ Anti-TNC BBB Shuttle Antibody(NRZP-1022-ZP2689)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; IHC; Inhib; In Vitro; In Vivo
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
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Host Species
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Fig.1 Specific binding of ST2485 to human tenascin and Tn (A (1-4) -D) fragments by Western blot analysis.
Vehicle versus 1 mg/kg, 3 mg/kg and 10 mg/kg C3 antibody. Data are presented as Mean±SEM. Statistical significances: ## p<0.01 and #### p<0.0001 when compared to Day 0, * p<0.05 and ** p<0.01 when compared to the vehicle-treated group.
Fig.2 Competition ELISA between ST2485 and BC-2 for binding to tenascin C fragment.
Vehicle versus 1 mg/kg, 3 mg/kg and 10 mg/kg C3 antibody. Data are presented as Mean±SEM. Statistical significances: ## p<0.01 and #### p<0.0001 when compared to Day 0, * p<0.05 and ** p<0.01 when compared to the vehicle-treated group.
Fig.3 Competition ELISA between ST2485 and BC-2 for binding to tenascin C fragment.
Vehicle versus 1 mg/kg, 3 mg/kg and 10 mg/kg C3 antibody. Data are presented as Mean±SEM. Statistical significances: ## p<0.01 and #### p<0.0001 when compared to Day 0, * p<0.05 and ** p<0.01 when compared to the vehicle-treated group.
Fig.4 In vivo additivity of antibodies ST2485 and ST2146, expressed in ng of antibody localized per gram of tumor.
Vehicle versus 1 mg/kg, 3 mg/kg and 10 mg/kg C3 antibody. Data are presented as Mean±SEM. Statistical significances: ## p<0.01 and #### p<0.0001 when compared to Day 0, * p<0.05 and ** p<0.01 when compared to the vehicle-treated group.
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