NeuroMab™ Mouse Anti-Human DRD4 Monoclonal Antibody (CBP2211)

Product Overview

Description

Dopamine Receptor D4 (DRD4) is a G-protein coupled receptor which inhibits adenyl cyclase activity. It is linked to many neurological and psychiatric conditions including schizophrenia and bipolar disorder, addictive behaviors, Parkinson's disease, and eating disorders such as anorexia nervosa. DRD4 mutations have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking.

Immunogen

A peptide corresponding to the 3rd extracellular domain of DRD4 (a.a. 176-185).

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2211

Applications

Application Notes

WB (0.5-2 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1637

Product Properties

Form

Liquid

Formulation

This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Handling Advice

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

DRD4

Official Name

DRD4

Full Name

Dopamine Receptor D4

Alternative Names

D(2C) dopamine receptor; D(4) dopamine receptor (D(2C) dopamine receptor); D(4) dopamine receptor; D4 dopamine receptor; D4DR
Dopamine D4 receptor; DRD 4; Drd4
DRD4