Product
NeuroMab™ Mouse Anti-Human DRD4 Monoclonal Antibody (CBP2211)
[CAT#: NAB201084LS]
Anti-DRD4 Monoclonal Antibody [HRP]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Dopamine Receptor D4 (DRD4) is a G-protein coupled receptor which inhibits adenyl cyclase activity. It is linked to many neurological and psychiatric conditions including schizophrenia and bipolar disorder, addictive behaviors, Parkinson's disease, and eating disorders such as anorexia nervosa. DRD4 mutations have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking.
Immunogen
A peptide corresponding to the 3rd extracellular domain of DRD4 (a.a. 176-185).
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP2211
Applications
WB
Application Notes
WB (0.5-2 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1637
Product Properties
Form
Liquid
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Handling Advice
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
DRD4
Official Name
DRD4
Full Name
Dopamine Receptor D4
Alternative Names
D(2C) dopamine receptor; D(4) dopamine receptor (D(2C) dopamine receptor); D(4) dopamine receptor; D4 dopamine receptor; D4DR
Dopamine D4 receptor; DRD 4; Drd4
DRD4
Dopamine D4 receptor; DRD 4; Drd4
DRD4
References
1. Pappa I, et al. 2015. Neurosci. Biobehav. Rev. 57:175.
2. Yildirim BO, Derksen JJ. 2015. Psychiatry Res. 229(3):633-77.
2. Yildirim BO, Derksen JJ. 2015. Psychiatry Res. 229(3):633-77.
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
