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Creative Biolabs
Product

NeuroMab™ Anti-NGFR, Mouse Monoclonal Antibody, Clone MC192 (CBP8820)

[CAT#: NRZP-0522-ZP213]

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
In-vivo

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Product Overview

Description

MC192-saporin is an antibody conjugate comprising of the monoclonal antibody MC192 against rat p75NTR, the nerve growth factor receptor, chemically conjugated via a reducible disulfide bridge to the ribosome-inactivating protein saporin, purified from saponaria officinalis.

Immunogen

Rat NGF receptor (p75NTR)

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP8820

Applications

In-vivo

Conjugation

Saporin
Product Properties

Form

Lyophilized from a 1 mg/mL solution containing PBS pH 7.2-7.6 without preservative.

Purity

Conjugate was purified by ion-exchange chromatography. Purity> 90% by non-reducing SDS-PAGE.

Shipping

25°C (ambient)

Storage

Lyophilized product is shipped at ambient room temperature. Upon receipt, pulse-centrifuge the vial to collect solid that may be entrapped in the lid. After reconstitution, immediately prepare aliquots and keep the undiluted stock at -80°C for long-term storage. Avoid repeated thaw-freezing. For short-term storage, keep at 2-8°C for up to 2 weeks. it is recommended to handle this product under sterile conditions.

Handling Advice

Spin vial briefly before opening. Reconstitute in sterile-filtered, ultrapure water to achieve a conjugate concentration of 1 mg/mL. Centrifuge to remove any insoluble material. Final buffer contains no preservatives.

Research Use Only

For research use only.
Target

Target

NGFR

Full Name

NGFR/p75 neurotrophin receptor (p75NTR)

Alternative Names

Low-affinity nerve growth factor receptor; NGF receptor; Gp80-LNGFR; p75 ICD; Low affinity neurotrophin receptor p75NTR; CD271

Uniprot ID

P07174 (TNR16_RAT);P20656 (RIP6_SAPOF)
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