Human CHO-K1/D5/Gα15 Stable Cell Line

[CAT#: NCL20120054CR]

D5 Dopamine Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

It plays multiple roles in the periphery as a modulator of cardiovascular function, catecholamine release, hormone secretion, vascular tone, renal function, and gastrointestinal motility. The dopamine receptor family consists of five members, which are classified into two groups, D1-like (D1 and D5) and D2-like (D2, D3, and D4). Dopamine receptor 2 is mainly expressed in the brain. It has splicing variants, D2L and D2S. D2R receptor is implicated in a number of neurological and psychiatric conditions.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

Family

Dopamine receptor

Strain

D5/Gα15 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

Official Name

Alternative Names

D5 receptor; D1B; DRD1L2; DRD1B; D(1B) dopamine receptor; Dopamine receptor D5; d(5) dopamine receptor; dopamine receptor 5; Drd-5; Gpcr1; D5R

Gene ID

1816(Human)

Uniprot ID

P21918(Human)

References

1. Chen, Z., Su, X., Shen, Y., Jin, Y., Luo, T., Kim, I. M.,.. & Tang, Y. (2019). MiR322 mediates cardioprotection against ischemia/reperfusion injury via FBXW7/notch pathway. Journal of molecular and cellular cardiology, 133, 67-74.

Publications