Human CHO-K1/GIP/Gα15 Stable Cell Line

[CAT#: NCL20120069CR]

Gastric Inhibitory Polypeptide Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

Gastric inhibitory polypeptide receptor (GIPR) is a Gs-coupled GPCR which is expressed in the pancreas, stomach, small intestine, adipose tissue, adrenal cortex, pituitary, heart, testis, endothelial cells, bone, trachea, spleen, thymus, lung, kidney, thyroid, and several regions in the CNS. Its ligand GIP is secreted after meal ingestion has been shown to stimulate bone formation resulting in lower occurrences of osteoporosis. GIPR may have therapeutic potential in the treatment of type 2 diabetes and obesity.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR; Neural Stem Cell

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

GIPR

Family

Glucagon receptor

Strain

GIP/Gα15 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

GIPR

Official Name

GIPR

Alternative Names

GIP receptor; Gippr; RATGIPPR; GIP-R; gastric inhibitory peptide receptor; gastric inhibitory polypeptide receptor; glucose-dependent insulinotropic polypeptide receptor; LOC232937; LOC381853; Gm1081; Gm160

Gene ID

2696(Human)

Uniprot ID

P48546(Human)

References

1. Zhang, W., Chen, L., Ma, Z., Du, L., & Li, M. (2014). Design, synthesis and biological evaluation of naphthalimidebased fluorescent probes for α1-adrenergic receptors. Drug Discoveries & Therapeutics, 8(1), 11-17.

Publications