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Creative Biolabs

NeuroMab™ Anti-SAP102 MAGUK scaffold protein BBB Shuttle Antibody, Clone N19/2

[CAT#: NRZP-0423-ZP375]

Species Reactivity:
Rat; Mouse; Human
Applications:
WB; IHC; IP; ICC

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Product Overview

Description

The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-SAP102 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.

Immunogen

Fusion protein amino acids 1-120 of rat SAP102 (accession number Q62936)
Human: 98% identity (117/120 amino acids identical)
Mouse=98% identity (118/120 amino acids identical)

Construction

We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.

Species Reactivity

Rat; Mouse; Human

Clonality

Monoclonal

Isotype

IgG1

Clone Number

N19/2

Applications

WB; IHC; IP; ICC

Application Notes

No crossreactivity against other MAGUK family members PSD-95, SAP97, Chapsyn-110

Research Areas

Scaffolds

Conjugation

Unconjugated
Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.
Target

Target

SAP102

Official Name

DLG3

Full Name

SAP102

Alternative Names

DLG3; MRX; MRX90; NEDLG; PPP1R82; SAP102; XLMR; discs large homolog 3; discs large MAGUK scaffold protein 3

Uniprot ID

Q62936
Publications

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