Product
NeuroMab™ Anti-SAP102 MAGUK scaffold protein BBB Shuttle Antibody, Clone N19/2
[CAT#: NRZP-0423-ZP375]
- Species Reactivity:
- Rat; Mouse; Human
- Applications:
- WB; IHC; IP; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-SAP102 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 1-120 of rat SAP102 (accession number Q62936)
Human: 98% identity (117/120 amino acids identical)
Mouse=98% identity (118/120 amino acids identical)
Human: 98% identity (117/120 amino acids identical)
Mouse=98% identity (118/120 amino acids identical)
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse; Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
N19/2
Applications
WB; IHC; IP; ICC
Application Notes
No crossreactivity against other MAGUK family members PSD-95, SAP97, Chapsyn-110
Research Areas
Scaffolds
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
SAP102
Official Name
DLG3
Full Name
SAP102
Alternative Names
DLG3; MRX; MRX90; NEDLG; PPP1R82; SAP102; XLMR; discs large homolog 3; discs large MAGUK scaffold protein 3
Uniprot ID
Q62936
Product Pictures
IHC
Fig. 1 Adult rat hippocampus immunohistochemistry.
IB
Fig. 2 Immunoblot versus adult rat brain membranes (RBM), and adult mouse hippocampal membranes (MHM) from SAP102 knockout and WT mice.
IB
Fig. 3 Adult rat brain membrane immunoblot.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
