NeuroMab™ Anti-Cleaved Notch1 (CBP14862)
[CAT#: NRZP-0922-ZP3551]
- Host Species:
- Rabbit
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IP; ChIP
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
The NeuroMab™ anti-Cleaved Notch1 (Val1744) antibody detects endogenous levels of the Notch1 intracellular domain (NICD) only when released by cleavage between Gly1753 and Val1754 (equivalent to Gly1743/Val1744 of murine notch1). The antibody does not recognize full-length Notch1 or Notch1 cleaved at other positions. The size of the NICD varies among cell lines due to mutations in the Notch1 C-terminus (6).
Expression Host
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence at the Val1754 cleavage site in human Notch1 (equivalent to Val1744 in mouse Notch1).
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Rabbit
Isotype
Rabbit IgG
Clone Number
CBP14862
Applications
WB; IP; ChIP
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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