NeuroMab™ Rat Anti-Trem-1 Monoclonal Antibody (CBP2592)
[CAT#: NAB2007FY1113]
Rat Monoclonal [NSB8.2A12.3A12] to Trem-1
- Host Species:
- Rat
- Species Reactivity:
- Mouse
- Applications:
- FC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Rat anti-Mouse Trem-1 antibody, recognizes the mouse trigger receptor expressed on myeloid cell 1 (TREM-1), the immunoglobulin superfamily expressed on neutrophils The 30kD member and part of monocytes. TREM-1 is involved in the inflammatory response of microorganisms. Together with the adaptor protein DAP12, it activates neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and the enhancement of inflammatory response. Microbial infection also induces the release of a soluble form of TREM-1 from monocytes, which is reported to be an inhibitor of TREM-1.
Immunogen
Mouse TREM-1 Fc fusion protein.
Species Reactivity
Mouse
Clonality
Monoclonal
Host Species
Rat
Isotype
IgG2a
Clone Number
CBP2592
Applications
FC
Application Notes
FC: 1/10
Relevant Diseases
Alzheimer's Disease; Neurodegenerative Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1885
Product Properties
Form
Liquid
Formulation
PBS, 0.09% Sodium Azide, 1% BSA
Preservatives
YES
Concentration
0.05 mg/ml
Purification
Protein G
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
TREM1
Official Name
TREM1
Full Name
TREM1 Gene(Protein Coding) Triggering Receptor Expressed On Myeloid Cells 1
Alternative Names
Triggering Receptor Expressed On Myeloid Cells 1; Triggering Receptor Expressed On Monocytes 1; TREM-1; CD354 Antigen; CD354;
References
1. Wang, F. et al. (2012) Blocking TREM-1 signaling prolongs survival of mice with Pseudomonas aeruginosa induced sepsis.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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