Product
Mouse Anti-RBFOX1 Monoclonal Antibody (CBP4301)
[CAT#: NAB210173LS]
Anti-RBFOX1 Monoclonal Antibody [Alexa Fluor 488 ]
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat
- Applications:
- IHC-P
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Rbfox1 is a member of the RNA binding protein family that shares a conservative RNA recognition motif. Rbfox1 has been shown to modulate alternative splicing by binding the consensus RNA sequence motif (U)GCAUG within introns. The interaction between cytoplasmic Rbfox1 and mRNA affects mRNA stability and translation. The binding of Rbfox1 protein to the C-terminus of ataxin-2 may be a contributing factor to the development of spinocerebellar ataxia type 2 .
Species Reactivity
Human; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP4301
Applications
IHC-P
Application Notes
IHC-P (5.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Alexa Fluor 488
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Wang ET, et al. 2016. J. Neurosci. 36(45):11418
2. Duan W, et al. 2016. Mol Neurobiol. 53(3):1637
3. Kuroyanagi H, 2009. Cell Mol Life Sci. 66(24):3895
2. Duan W, et al. 2016. Mol Neurobiol. 53(3):1637
3. Kuroyanagi H, 2009. Cell Mol Life Sci. 66(24):3895
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
