Mouse Anti-HSP60 Monoclonal Antibody (CBP6710)
[CAT#: NAB2007FY1571]
Mouse Monoclonal to HSP60
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat; Mouse
- Applications:
- WB; IF; IHC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
As the name suggests, heat shock proteins were discovered because they are severely upregulated when cells are subjected to a temperature pressure higher than the normal physiological range. They are also expressed in unstressed cells and have normal functions as partners, helping other proteins to fold correctly. If cells or tissues are subjected to heat stress, the demand for molecular chaperones will be greater, so these proteins will be severely upregulated. Different heat shock proteins were originally named based on their SDS-PAGE mobility, so the apparent molecular weight of HSP60 is 60kDa. It is a rich protein in mitochondria and is usually responsible for the transport and refolding of proteins from the cytoplasm into the mitochondrial matrix. HSP60 is a homologue of the well-studied bacterial chaperone GroEL, and both are ATPases (1,2).
Immunogen
Spontaneous autoantibodies, binding to LNERLAKLSDGVAVLKVGGT, amino acids 390-409 of the human sequence
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP6710
Applications
WB; IF; IHC
Application Notes
WB: 1:10000
ICC/IF and IHC: 1:5000
ICC/IF and IHC: 1:5000
Product Properties
Form
Liquid
Formulation
50% PBS, 50% glycerol
Preservatives
5mM NaN3
Concentration
1 mg/ml
Shipping
Gel Pack
Storage
Store at 4°C for short term, for longer term at -20°C
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Target
HSP60
Official Name
HSBD1
Alternative Names
HSBD1; HSP60
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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