NeuroMab™ Anti-Fas, Mouse Monoclonal Antibody, Clone R-125224 (CBP8858)

[CAT#: NRZP-0522-ZP286]

Host Species:: Rabbit

Species Reactivity:: Human

Applications:: Activ; ELISA; FC

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Product Overview

Description

Rabbit anti-Fas Recombinant Antibody (Unconjugated), suitable for Activate, ELISA, FC.

Immunogen

R-125224 is generated by the humanization of the murine HFE7A anti-Fas antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423).

Species Reactivity

Human

Clonality

Recombinant

Host Species

Rabbit

Isotype

IgG, kappa

Clone Number

CBP8858

Applications

Activ; ELISA; FC

Conjugation

Unconjugated

Product Properties

Form

Liquid. PBS with 0.02% Proclin 300.

Concentration

1 mg/mL

Purity

Purified antibody, via affinity chromatography

Shipping

2-8°C (on cold packs)

Storage

Store at 2-8°C for up to 1 month. For longer storage, aliquot and store at -20_C. Avoid mulitiple freeze thaw cycles.

Research Use Only

For research use only.

Target

Fas

Full Name

Fas

Alternative Names

CD95; h-HFE7A; Tumor necrosis factor receptor superfamily member 6; CD-95; Apo-1; Apo 1; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor