Human CHO-K1/PRLHR Stable Cell Line

[CAT#: NCL20120114CR]

Prolactin-releasing Peptide Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

The prolactin releasing hormone receptor PRLHR also named PrRP receptor is a G-protein coupled receptor that binds the prolactin releasing hormone. RT-PCR analysis showed expression of PRLHR in the human brain, pituitaries, normal portions of adrenal glands and various tumor tissues. Northern blot analysis showed high expression of PRLHR only in tumor tissues of pheochromocytomas, indicating that PRLHR expression is high in pheochromocytomas. The present study has shown that PRLHR mRNA was widely expressed in the brain tissues, pituitaries, adrenal glands and various tumors. The high expression of PRLHR receptor in pheochromocytomas suggests potential pathophysiological roles of PRLHR in these tumors

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 400 μg/ml G418

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

PRLHR

Family

Prolactin releasing peptide receptor

Strain

PRLHR Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

PRLHR

Official Name

PRLHR

Alternative Names

PRRP receptor; PrRPR; PrRP-R; PRLHR; hGR3; UHR-1; GPR10; G protein-coupled receptor 10; prRP receptor; prolactin releasing hormone receptor; GR3; Gm339

Gene ID

2834(Human); 226278(Mouse); 246075(Rat)

Uniprot ID

P49683(Human); Q6VMN6(Mouse); Q64121(Rat)

References

1. Mi, G., Liu, S., Zhang, J., Liang, H., Gao, Y., Li, N.,.. & Yang, Z. (2017). Levo-tetrahydroberberrubine produces anxiolytic-like effects in mice through the 5-HT 1A receptor. PloS one, 12(1), e0168964.

Publications