NeuroMab™ Anti-EPHA2 BBB Shuttle Antibody,Clone NR3831P

Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Clone Number

NR3831P

Applications

ELISA

Relevant Diseases

Glioblastoma Multiforme

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

EPHA2

Official Name

EPHA2

Full Name

EPH receptor A2 (ephrin type-A receptor 2)

Alternative Names

EPHA2; Epha2; AW545284; Eck; Myk2; Sek-2; Sek2; ARCC2; CTPA; CTPP1; CTRCT6; EPH receptor A2; ECK

Product Pictures

ELISA

Figure 1 shows the reactivity when SHM41, 57-1 or 230-1 was used as supplementary antibody and biotin-labeled 57-1 or 230-1 was used as detection antibody.

ELISA

Figure 2 is an amino acid sequence diagram of the CDRs of the mouse anti-EPHA2 monoclonal antibody 230-1.

ELISA

Figure 3 shows the amino acid sequence of the CDRs of the mouse anti-EPHA2 monoclonal antibody 57-1.

ELISA

Figure 4 shows the reactivity of the ELISA system to EPHA2 (supplementary antibody 230-1 and detection antibody biotinylated 57-1, supplementary antibody 57-1 and detection antibody biotinylated 230-1).