NeuroMab™ Anti-SEZ6 BBB Shuttle Antibody(NRZP-1022-ZP2437)
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat; Cynomolgus Monkey
- Applications:
- FC; IHC; In Vitro; In Vivo
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Research Use Only
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Fig.1 shows the expression of SEZ6 in HEK-293T cells modified to overexpress human SEZ6 protein (h293T-HuSEZ6) using anti-SEZ6 antibody SC17.33.
The X axis corresponds to the concentration of 3E antibody (Fab) and the Y axis corresponds to NGF binding (percentage of maximum UR). Increased concentrations of Fab E3 blocked the interaction of NGF with both p75 and trkA, as shown by signal reduction (measured in UR). When the concentration of E3 antibody (Fab) was equalized with the concentration of NGF, no NGF binding was observed (as shown by a zero signal).
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