NeuroMab™ Anti-Notch1 Antibody, Clone N585 (CBP14861)
[CAT#: NRZP-0922-ZP3550]
- Host Species:
- Rabbit
- Species Reactivity:
- Human
- Applications:
- WB
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SPECIFIC INQUIRY
inquiryProduct Overview
Description
The NeuroMab™ anti-Notch1 antibody detects intracellular epitopes between 2400 and 2500 amino acids of human Notch1. It recognizes both the full-length (~300 KDa) and the NTM region (~120 KDa), which consists of a short extracellular juxtamembrane peptide, a transmembrane sequence and the intracellular domain (NICD). The antibody cannot detect the extracellular (ligand-binding) domain of Notch1 following cleavage at the S2 site by ADAM-type metalloproteases.
Expression Host
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro2439 of human Notch1.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Rabbit
Isotype
Rabbit IgG
Clone Number
CBP14861
Applications
WB
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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