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Creative Biolabs

NeuroMab™ Mouse Anti-PPP2R2A Monoclonal Antibody (CBP2217)

[CAT#: NAB2010103LS]

Anti-PPP2R2A Monoclonal Antibody [HRP]

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB

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Product Overview

Description

Protein phosphatase 2A is a heterotrimeric protein serine/threonine phosphatase consisting of a 36-kD catalytic C subunit (alpha and beta isoforms), a 65-kD structural A subunit (alpha and beta isoforms), and a variable regulatory B subunit. When the PP2A catalytic C subunit associates with the A and B subunits several species of holoenzymes are produced with distinct functions and characteristics. Ubiquitously expressed, PP2A is involved in a broad range of cellular processes, including membrane receptor desensitization, signal transduction, intermediary metabolism, transcriptional regulation and control of DNA replication, and mitosis.

Immunogen

A synthetic peptide corresponding to residues surrounding Asp406 of rat PP2R2A/PP2A, B55-α/PR55-α protein.

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2217

Applications

WB

Application Notes

WB (2.0-5.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1643
Product Properties

Form

Liquid

Formulation

This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Handling Advice

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

PPP2R2A

Official Name

PPP2R2A

Full Name

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

Alternative Names

PPP2R2A; B55A; B55ALPHA; PR52A; PR55A; protein phosphatase 2 regulatory subunit Balpha; PR55alpha

Gene ID

26472(Human); 18938(Mouse); 259225(Rat)

Uniprot ID

Q96C90(Human); Q62084(Mouse); Q8K3F3(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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