NeuroMab™ Mouse Anti-Dynein Monoclonal Antibody (CBP2243)

[CAT#: NAB2010153LS]

Anti-Dynein Monoclonal Antibody [Alexa Fluor 594]

Host Species:: Mouse

Species Reactivity:: Vertebrate; Drosophila

Applications:: ICC

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Product Overview

Description

Dyneins are motor proteins that transport various cellular cargo along cytoskeletal microtubules in eukaryotic cells. Dynein has the same basic structures in all cell types and is composed of two or three distinct heavy chains (450 kD), three intermediate chains (70-125 kD), and at least four light chains (15-25 kD). The cytoplasmic dynein intermediate chain is thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.

Immunogen

Purified bovine brain cytoplasmic dynein.

Species Reactivity

Vertebrate; Drosophila

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2243

Applications

ICC

Application Notes

ICC (2.5-5 μg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1664

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

Handling Advice

The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Dynein

Official Name

Dynein

Full Name

Cytoplasmic Dynein Intermediate Chain

Alternative Names

Dynein light chain roadblock-type 1; Roadblock-1; ROBL/LC7-like 1; bithoraxoid-like protein; roadblock domain containing 1; dynein-associated protein Km23; cytoplasmic dynein light chain 2A; dynein light chain 2A; cytoplasmic

Publications