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Creative Biolabs

Anti-CD51 Monoclonal Antibody (CBP3934)

[CAT#: NAB2012726LS]

Anti-CD51 Monoclonal Antibody [Alexa Fluor 647 ]

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
FC

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Product Overview

Description

CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor α chain, or integrin αV. It forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands.

Immunogen

Human small cell lung carcinoma cells (UCLA P3).

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3934

Applications

FC

Application Notes

FCM (5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD51

Official Name

ITGAV

Full Name

Integrin alpha V

Alternative Names

ITGAV; CD51; MSK8; VNRA; VTNR; integrin subunit alpha V

Gene ID

3685 (Human); 16410 (Mouse)

Uniprot ID

P06756 (Human); P43406 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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