Human CHO-K1/GALR1/Gα15 Stable Cell Line

[CAT#: NCL20120062CR]

GAL1 Galanin Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Request Pricing

Inquiry

Product Overview

Description

The neuropeptide galanin elicits a range of biological effects by interacting with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins that have been shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain, spinal cord, and peripheral sites including small intestine and heart.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 100 μg/ml Hygromycin B, and 200 μg/ml Zeocin

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

GALR1

Family

Galanin receptor

Strain

GALR1/Gα15 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

GALR1

Official Name

GALR1

Alternative Names

GAL1 receptor; Galanin-1 receptor; GALR1; GALNR1; GALNR; GAL1-R; GALR-1; galanin receptor type 1

Gene ID

2587(Human); 14427(Mouse); 50577(Rat)

Uniprot ID

P47211(Human); P56479(Mouse); Q62805(Rat)

References

1. Shembekar, N., Mallajosyula, V. V. A., Mishra, A., Yeolekar, L., Dhere, R., Kapre, S.,.. & Gupta, S. K. (2013). Isolation of a high affinity neutralizing monoclonal antibody against 2009 pandemic H1N1 virus that binds at the 'Sa'antigenic site. PLoS One, 8(1), e55516.

Publications