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Creative Biolabs

Human CHO-K1/OPRD1/Gα15 Stable Cell Line

[CAT#: NCL20120099CR]

δ-Opioid Receptor OPRD1 Stable Cell Line

Species:
Human
Applications:
GPCR Screening
Cell Types:
Other Cells

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Product Overview

Description

Opioid receptor family includes three classic receptors, μ, δ, and κ, also known as OP1, OP2 and OP3, respectively. The receptors are Gi/o-coupled GPCRs which will reduce intracellular cAMP levels after activation. δ-opioid receptor modulates many kinase cascades including ERKs, Akts, JNKs, STAT3, P38 involving Src, Ras, Rac, Raf-1, Cdc42, RTKs. In addition, δ-opioid receptor has also been proposed to interact with μ receptors. The observed pharmacological cross-talk may partially arise from agonist cross-reactivity.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human
Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 200 μg/ml Zeocin, 100 μg/ml Hygromycin B

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

OPRD1

Family

Opioid & opioid-like receptor

Strain

OPRD1/Gα15 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target Details

Target

Delta Opioid Receptor

Official Name

OPRD1

Alternative Names

DOR; OP1; DOP; Delta opioid receptor; Opioid receptor delta 1; delta-type opioid receptor; opioid receptor A; Nbor; mDOR; DOP-r

Gene ID

4985(Human); 18386(Mouse); 24613(Rat)

Uniprot ID

P41143(Human); P32300(Mouse); P33533(Rat)
Publications

Publications (0)

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